ALKBH5-mediated m6A demethylation of TXNDC5 drives malignant progression in gastric cancer
Our findings demonstrate that the ALKBH5-TXNDC5 axis drives GC progression through m6A-dependent regulation, highlighting ALKBH5 as a potential therapeutic target for GC.
Authors
- Feifei Zhou (ORCID: https://orcid.org/0000-0003-3905-7760)
- Weiqun Peng (ORCID: https://orcid.org/0000-0001-5521-9091)
- Xiaoquan Wei
- Hongwei Xu (ORCID: https://orcid.org/0000-0002-7631-1126)
Institutions
- Nanjing Drum Tower Hospital (CN)
- Shandong Provincial Hospital (CN)
- Shandong First Medical University (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Epigenomics
- Published
- 2025-11-11
- DOI
- https://doi.org/10.1080/17501911.2025.2586450
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00