Ethical AI in Healthcare: Integrating Zero-Knowledge Proofs and Smart Contracts for Transparent Data Governance

In today's rapidly advancing healthcare landscape, integrating Artificial Intelligence (AI) and Machine Learning (ML) has the potential to significantly improve patient care and streamline medical processes. The utilization of confidential patient data to train and develop these technologies, however, raises significant concerns regarding authenticity, security, and privacy. In this study, we introduce MediChainAI, a safe and practical framework that allows patients full ownership over their own health data by integrating Self-Sovereign Identity (SSI), Blockchain, and sophisticated cryptography techniques. By clearly outlining the goals and parameters of this access, MediChainAI allows patients to safely and selectively share data with healthcare providers and researchers. While SSI guarantees that patients have ownership of their data, the framework uses Blockchain technology to keep things transparent and secure. Further, MediChainAI makes use of Merkle trees, which provide verified access to subsets of data without jeopardizing the privacy of the whole dataset. The encryption mechanism, which is based on smart contracts, is a distinctive feature of the framework that allows researchers and medical practitioners controlled and secure access to patient data. In order to improve the accuracy and reliability of medical diagnoses and treatment, this strategy makes sure that only confirmed, legitimate data is utilized to train medical models. A significant step toward safer and more personalized healthcare, MediChainAI encourages ethical and patient-focused innovation by effectively resolving essential issues regarding data security and patient privacy.

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Publication Details

Journal
Bioengineering
Published
2025-11-12
DOI
https://doi.org/10.3390/bioengineering12111236
Citations
2
Primary Topic
Blockchain Technology Applications and Security
Type
article
Field-Weighted Citation Impact
6.49
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article

Ethical AI in Healthcare: Integrating Zero-Knowledge Proofs and Smart Contracts for Transparent Data Governance

Ayman Mohamed Mostafa, Mohamed Ezz, Alaa Alaerjan
2 citations
Bioengineering
Blockchain Technology Applications and Security
6.49
article

Ethical AI in Healthcare: Integrating Zero-Knowledge Proofs and Smart Contracts for Transparent Data Governance

Ayman Mohamed Mostafa, Mohamed Ezz, Alaa Alaerjan
article en
2 citations

Abstract

In today's rapidly advancing healthcare landscape, integrating Artificial Intelligence (AI) and Machine Learning (ML) has the potential to significantly improve patient care and streamline medical processes. The utilization of confidential patient data to train and develop these technologies, however, raises significant concerns regarding authenticity, security, and privacy. In this study, we introduce MediChainAI, a safe and practical framework that allows patients full ownership over their own health data by integrating Self-Sovereign Identity (SSI), Blockchain, and sophisticated cryptography techniques. By clearly outlining the goals and parameters of this access, MediChainAI allows patients to safely and selectively share data with healthcare providers and researchers. While SSI guarantees that patients have ownership of their data, the framework uses Blockchain technology to keep things transparent and secure. Further, MediChainAI makes use of Merkle trees, which provide verified access to subsets of data without jeopardizing the privacy of the whole dataset. The encryption mechanism, which is based on smart contracts, is a distinctive feature of the framework that allows researchers and medical practitioners controlled and secure access to patient data. In order to improve the accuracy and reliability of medical diagnoses and treatment, this strategy makes sure that only confirmed, legitimate data is utilized to train medical models. A significant step toward safer and more personalized healthcare, MediChainAI encourages ethical and patient-focused innovation by effectively resolving essential issues regarding data security and patient privacy.

BioengineeringVol. 12(11)
Jouf University (SA)
Openalex Percentile: Top 3%
Blockchain Technology Applications and Security
6.49
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Ethical AI in Healthcare: Integrating Zero-Knowledge Proofs and Smart Contracts for Transparent Data Governance — Ayman Mohamed Mostafa, Mohamed Ezz, et al. · Bioengineering (2025) | TGRS Research Map | TGRS