Dimethylarginines in pediatric CKD: clinical utility of ADMA and SDMA as biomarkers
Serum ADMA and SDMA levels increase with worsening kidney function in children and may serve as useful markers associated with disease severity in pediatric CKD, but further validation is required. In particular, ADMA reflects disease severity and endothelial dysfunction, highlighting its potential role in clinical risk stratification.
Authors
- Hülya Nalçacıoğlu (ORCID: https://orcid.org/0000-0002-0686-9714)
- Demet Tekcan Karalı
- Murat Cihan (ORCID: https://orcid.org/0000-0001-6611-7226)
- Hülya Gözde Önal (ORCID: https://orcid.org/0000-0003-4414-9598)
Institutions
- Ondokuz Mayıs University (TR)
- Ordu University (TR)
Publication Details
- Journal
- Frontiers in Pediatrics
- Published
- 2025-11-12
- DOI
- https://doi.org/10.3389/fped.2025.1662259
- Primary Topic
- Nitric Oxide and Endothelin Effects
- Type
- article
- Field-Weighted Citation Impact
- 0.00