Identification of ferroptosis-genes associated with pediatric inflammatory bowel disease bioinformatics and machine learning approaches
PML and CHAC1 are promising biomarkers for early PIBD diagnosis. These findings, supported by both bioinformatic analyses and experimental validation, may improve diagnostic accuracy and provide insights into the immune microenvironment and therapeutic strategies.
Authors
- Mei Yang (ORCID: https://orcid.org/0000-0002-3015-6036)
- Zhaoxiu Liu (ORCID: https://orcid.org/0000-0003-0154-5232)
- Liming Mao (ORCID: https://orcid.org/0000-0002-9740-820X)
- Zhen Xu (ORCID: https://orcid.org/0000-0002-2325-6514)
- Chun‐Quan Ou (ORCID: https://orcid.org/0000-0001-6866-7213)
Institutions
- Nantong University (CN)
- Affiliated Hospital of Nantong University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-11-12
- DOI
- https://doi.org/10.3389/fimmu.2025.1619944
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00