Effectiveness and safety of tenofovir alafenamide in chronic hepatitis B patients over 30 years old with positive hepatitis B virus DNA: a double-center retrospective study
TAF treatment significantly alleviated the progression of CHB patients over a 96-week follow-up period. TAF remains effective for younger patients or those with normal liver function, providing evidence for further expanding antiviral indications.
Authors
- Xuanxuan Wang
- Du Fan (ORCID: https://orcid.org/0000-0003-2704-2131)
- Shaoyuan Shi (ORCID: https://orcid.org/0009-0000-5558-7417)
- Li Zhou (ORCID: https://orcid.org/0000-0002-6736-0057)
- Zehong Wang (ORCID: https://orcid.org/0009-0006-2994-6125)
- Yinong Feng
Institutions
- Union Hospital (HK)
- Fourth People's Hospital of Taiyuan (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2025-11-12
- DOI
- https://doi.org/10.3389/fmed.2025.1680839
- Primary Topic
- Hepatitis B Virus Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00