Research progress on risk factors for in-stent restenosis following cerebrovascular stent implantation

Transient ischemic attack or ischemic stroke within 6 months is frequently associated with severe carotid stenosis. Carotid stent implantation is a widely employed treatment, but in-stent restenosis (ISR) is a dangerous postoperative complication. Many factors cause in-stent restenosis. Previous studies have indicated that stent type, drug use, patient-specific risk factors, levels of various factors in the patient's body, surgical procedures, and vascular physiological anatomy can all contribute to its occurrence. This review summarizes the key risk factors for ISR following CAS and briefly discusses related findings in intracranial artery stenting, aiming to inform clinical decision-making in neurointerventional practice.

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Publication Details

Journal
Frontiers in Neurology
Published
2025-11-12
DOI
https://doi.org/10.3389/fneur.2025.1660202
Primary Topic
Cerebrovascular and Carotid Artery Diseases
Type
article
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article

Research progress on risk factors for in-stent restenosis following cerebrovascular stent implantation

Guofang Yang, Yiwei Zhang, Jiabing Wang, Hongtu Tan et al.
Frontiers in Neurology
Cerebrovascular and Carotid Artery Diseases
article

Research progress on risk factors for in-stent restenosis following cerebrovascular stent implantation

Guofang Yang, Yiwei Zhang, Jiabing Wang, Hongtu Tan, Tao Wu, Haobo Gao, H Bibi
article en

Abstract

Transient ischemic attack or ischemic stroke within 6 months is frequently associated with severe carotid stenosis. Carotid stent implantation is a widely employed treatment, but in-stent restenosis (ISR) is a dangerous postoperative complication. Many factors cause in-stent restenosis. Previous studies have indicated that stent type, drug use, patient-specific risk factors, levels of various factors in the patient's body, surgical procedures, and vascular physiological anatomy can all contribute to its occurrence. This review summarizes the key risk factors for ISR following CAS and briefly discusses related findings in intracranial artery stenting, aiming to inform clinical decision-making in neurointerventional practice.

Frontiers in NeurologyVol. 16
Henan University of Traditional Chinese Medicine (CN), First Affiliated Hospital of Henan University (CN)
Openalex Percentile: Top 51%
Cerebrovascular and Carotid Artery Diseases
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Research progress on risk factors for in-stent restenosis following cerebrovascular stent implantation — Guofang Yang, Yiwei Zhang, et al. · Frontiers in Neurology (2025) | TGRS Research Map | TGRS