AdipoRon promotes angiogenesis in B-cell leukemia by modulating pro-angiogenic factors through AdipoR1
Our findings demonstrated that AdipoRon promotes angiogenesis in B-cell leukemia by enhancing pro-angiogenic factors through AdipoR1highlighting adiponectin's significance in angiogenesis. A better understanding of adiponectin's mechanisms could facilitate the development of therapeutic strategies targeting its pathway to inhibit tumor angiogenesis, offering promising approaches for leukemia treatment. Further studies are needed to fully explore adiponectin potential in leukemia.
Authors
- Angela Chambery (ORCID: https://orcid.org/0000-0002-5136-0941)
- Rosita Russo (ORCID: https://orcid.org/0000-0002-2235-6302)
- Marta Mallardo (ORCID: https://orcid.org/0000-0002-7482-2205)
- Ersilia Nigro (ORCID: https://orcid.org/0000-0001-5637-1685)
- Aurora Daniele (ORCID: https://orcid.org/0000-0002-9085-9737)
Institutions
- Federico II University Hospital (IT)
- University of Campania "Luigi Vanvitelli" (IT)
- CEINGE Biotecnologie Avanzate Franco Salvatore (Italy) (IT)
- University of Naples Federico II (IT)
Publication Details
- Journal
- Molecular Biology Reports
- Published
- 2025-11-11
- DOI
- https://doi.org/10.1007/s11033-025-11183-x
- Primary Topic
- Adipokines, Inflammation, and Metabolic Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Università degli Studi di Napoli Federico II