Supracardiac Atherosclerotic Lesions in Embolic Stroke of Undetermined Source: Predicting Stroke Recurrence and Enhancing Secondary Prevention Strategies

Intracranial nonrelevant stenosis and complex aortic atheroma, along with cardioembolic factors like paroxysmal atrial fibrillation and atrial septal aneurysm, are key predictors of stroke recurrence in embolic stroke of undetermined source, especially those without moderate-risk cardioembolic sources. These findings emphasize the need to consider both supracardiac atherosclerotic and cardioembolic mechanisms in embolic stroke of undetermined source and to develop tailored secondary prevention strategies for atherosclerotic stroke, particularly in cases with supracardiac atherosclerotic lesions to reduce stroke recurrence.

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Publication Details

Journal
Journal of the American Heart Association
Published
2025-11-12
DOI
https://doi.org/10.1161/jaha.125.042812
Primary Topic
Aortic Thrombus and Embolism
Type
article
Field-Weighted Citation Impact
0.00
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article

Supracardiac Atherosclerotic Lesions in Embolic Stroke of Undetermined Source: Predicting Stroke Recurrence and Enhancing Secondary Prevention Strategies

Ho Geol Woo, Jang‐Hyun Baek, Sung‐A Chang, Min Kyoung Kang et al.
Journal of the American Heart Association
Aortic Thrombus and Embolism
article

Supracardiac Atherosclerotic Lesions in Embolic Stroke of Undetermined Source: Predicting Stroke Recurrence and Enhancing Secondary Prevention Strategies

Ho Geol Woo, Jang‐Hyun Baek, Sung‐A Chang, Min Kyoung Kang, Hyun-Kyung Kim, Hahn Young Kim, Jee‐Hyun Kwon, Kwang‐Yeol Park, Gyeong‐Moon Kim, Ji Sung Lee, Man‐Seok Park, Hyo Suk Nam, Oh Young Bang, Jin‐Man Jung, Moo‐Seok Park, Woo‐Keun Seo, Chi Kyung Kim, Chul‐Hoo Kang, Wook‐Ju Kim, Joong‐Goo Kim, Sung‐Il Sohn, Jae‐Kwan Cha, Sung Hyuk Heo, Hee‐Joon Bae, Jong‐Won Chung, Kang‐Ho Choi, Jay Chol Choi, Young Seo Kim, Hee‐Kwon Park, Sun U. Kwon, Tae‐Jin Song, Hyungjong Park, Yang‐Ha Hwang, Sang Hun Lee, Hyung Jun Kim, Beom Joon Kim, Bum Joon Kim
article en

Abstract

Intracranial nonrelevant stenosis and complex aortic atheroma, along with cardioembolic factors like paroxysmal atrial fibrillation and atrial septal aneurysm, are key predictors of stroke recurrence in embolic stroke of undetermined source, especially those without moderate-risk cardioembolic sources. These findings emphasize the need to consider both supracardiac atherosclerotic and cardioembolic mechanisms in embolic stroke of undetermined source and to develop tailored secondary prevention strategies for atherosclerotic stroke, particularly in cases with supracardiac atherosclerotic lesions to reduce stroke recurrence.

Journal of the American Heart AssociationVol. 14(22)
Ulsan College (KR), Ewha Womans University (KR), Yonsei University (KR), Korea University (KR), Konkuk University (KR), Korea University Medical Center (KR), Dong-A University Hospital (KR), Kyungpook National University Hospital (KR), Asan Medical Center (KR), Samsung Medical Center (KR), Seoul National University Bundang Hospital (KR), Ansan University (KR), University of Ulsan (KR), Konkuk University Medical Center (KR), Chonnam National University Hospital (KR), Kangbuk Samsung Hospital (KR), Kyung Hee University Medical Center (KR), Ulsan University Hospital (KR), Inha University Hospital (KR), Jeju National University Hospital (KR), Hanyang University (KR), Keimyung University (KR), Chung-Ang University (KR), Sungkyunkwan University (KR)
Openalex Percentile: Top 51%
Aortic Thrombus and Embolism
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