Meta-analysis of the efficacy of neoadjuvant immunotherapy combined with radiotherapy and chemotherapy for locally advanced rectal cancer
The addition of neoadjuvant immunotherapy improved the clinical remission rate of patients who had LARC with pMMR, and the treatment-related adverse reactions were generally acceptable. Neoadjuvant immunotherapy combined with radiotherapy and chemotherapy should be considered for patients with LARC.
Authors
- Wen-Xing Yan
- Lijuan Qin
- Juan Wu (ORCID: https://orcid.org/0000-0002-2580-9936)
- N. Li (ORCID: https://orcid.org/0009-0006-3218-8548)
- Jia Li (ORCID: https://orcid.org/0000-0003-4226-0292)
- Juan He (ORCID: https://orcid.org/0000-0003-2134-9415)
- Jie Mu (ORCID: https://orcid.org/0000-0003-3466-238X)
- Zeyi Xiong
- Helen Yuan
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Shanxi Provincial Cancer Hospital (CN)
Publication Details
- Journal
- World Journal of Gastrointestinal Oncology
- Published
- 2025-11-12
- DOI
- https://doi.org/10.4251/wjgo.v17.i11.113048
- Primary Topic
- Colorectal and Anal Carcinomas
- Type
- article
- Field-Weighted Citation Impact
- 0.00