Nanofibrous Coatings of Poly(Lactic Acid) and Nano‐Hydroxyapatite for Enhanced Biocompatibility of Titanium Implants

ABSTRACT Electrospun nanofibrous coatings based on poly(lactic acid) (PLA) and bioactive nano‐hydroxyapatite (nHAp) are developed to enhance the biocompatibility and corrosion resistance of titanium implants for medical applications. The electrospinning process parameters are optimized to achieve a uniform morphology of PLA nanofibers and PLA/nHAp composite fibers. The morphology and porosity of the fiber coatings were investigated by scanning electron microscopy. FTIR spectroscopy confirms the successful incorporation of nHAp into the PLA fibers, while electrochemical impedance spectroscopy demonstrates a significant improvement in corrosion resistance for the nanocomposite‐coated titanium. Results show that the PLA/nHAp composite coatings prepared by electrospinning have promising features for applications in orthopedic and dental implantology.

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Publication Details

Journal
Macromolecular Symposia
Published
2025-11-11
DOI
https://doi.org/10.1002/masy.70248
Citations
1
Primary Topic
Electrospun Nanofibers in Biomedical Applications
Type
article
Field-Weighted Citation Impact
0.60

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article

Nanofibrous Coatings of Poly(Lactic Acid) and Nano‐Hydroxyapatite for Enhanced Biocompatibility of Titanium Implants

Maria Gabriella Santonicola, Elisa Toto, Gianluca Ciarleglio, L. Ferri et al.
1 citations
Macromolecular Symposia
Electrospun Nanofibers in Biomedical Applications
0.60
article

Nanofibrous Coatings of Poly(Lactic Acid) and Nano‐Hydroxyapatite for Enhanced Biocompatibility of Titanium Implants

Maria Gabriella Santonicola, Elisa Toto, Gianluca Ciarleglio, L. Ferri, Letizia Pagani
article en
1 citations

Abstract

ABSTRACT Electrospun nanofibrous coatings based on poly(lactic acid) (PLA) and bioactive nano‐hydroxyapatite (nHAp) are developed to enhance the biocompatibility and corrosion resistance of titanium implants for medical applications. The electrospinning process parameters are optimized to achieve a uniform morphology of PLA nanofibers and PLA/nHAp composite fibers. The morphology and porosity of the fiber coatings were investigated by scanning electron microscopy. FTIR spectroscopy confirms the successful incorporation of nHAp into the PLA fibers, while electrochemical impedance spectroscopy demonstrates a significant improvement in corrosion resistance for the nanocomposite‐coated titanium. Results show that the PLA/nHAp composite coatings prepared by electrospinning have promising features for applications in orthopedic and dental implantology.

Macromolecular SymposiaVol. 414(6)
Sapienza University of Rome (IT)
Sapienza Università di Roma
Openalex Percentile: Top 27%
Electrospun Nanofibers in Biomedical Applications
0.60
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