Incidence and risk factors of abnormal liver function and anti-tuberculosis drug-induced liver injury: a multicenter retrospective study involving 482 chinese pediatric tuberculosis patients
The incidence of abnormal liver function and ATDILI differed. By considering laboratory indicators and clinical practice, early identification and detection of abnormal liver function in children during anti-TB treatment, along with timely intervention, can effectively prevent and control the harm caused by abnormal liver function and prevent it progression to ATDILI.
Authors
- Yang Guangxu
- Lisu Huang (ORCID: https://orcid.org/0000-0001-8193-7353)
- Haiyan Li (ORCID: https://orcid.org/0000-0002-5541-3035)
- Bin Chen (ORCID: https://orcid.org/0000-0002-3544-5056)
- Ping Liu (ORCID: https://orcid.org/0000-0002-6152-4508)
- Fei Wang (ORCID: https://orcid.org/0000-0001-8997-8619)
- Tao Yang (ORCID: https://orcid.org/0000-0001-6375-3622)
- Xin Yu (ORCID: https://orcid.org/0000-0002-3762-2191)
- Yiqing Zhou (ORCID: https://orcid.org/0000-0002-6391-3259)
- Hongmei Xu (ORCID: https://orcid.org/0000-0003-2088-1960)
- Qingshan Cai (ORCID: https://orcid.org/0000-0002-2611-7640)
- Juan Ma
- Man Tian (ORCID: https://orcid.org/0009-0004-6218-4631)
- Xianhui Zeng
- Qing Fang
- Min Wang (ORCID: https://orcid.org/0000-0003-2052-199X)
Institutions
- Qingdao University (CN)
- Wenzhou Medical University (CN)
- Qinghai No.3 People's Hospital (CN)
- Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University (CN)
- Red Cross Hospital (GR)
- Ningbo No. 2 Hospital (CN)
- Shanghai Public Health Clinical Center (CN)
- Heilongjiang Center for Tuberculosis Control and Prevention (CN)
- Hainan Modern Women and Children's Hospital (CN)
- Children's Hospital of Zhejiang University (CN)
- Changchun Obstetrics and Gynecology Hospital (CN)
- Children's Medical Center (US)
- Changchun 208 Hospital (CN)
- Zhejiang Center for Disease Control and Prevention (CN)
- Second Affiliated Hospital of Nanjing Medical University (CN)
- Taiwan Centers for Disease Control (TW)
- Guangdong Province Women and Children Hospital (CN)
- Zhejiang Pharmaceutical College (CN)
- Hangzhou Red Cross Hospital (CN)
- Children's Hospital of Chongqing Medical University (CN)
- Zhejiang Medicine (China) (CN)
- Ningbo No.6 Hospital (CN)
- The Fifth People’s Hospital of Suzhou (CN)
- Hangzhou Medical College (CN)
- Qingdao Women and Children's Hospital (CN)
- Hainan Medical University (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Annals of Medicine
- Published
- 2025-11-11
- DOI
- https://doi.org/10.1080/07853890.2025.2546701
- Primary Topic
- Drug-Induced Hepatotoxicity and Protection
- Type
- article
- Field-Weighted Citation Impact
- 0.00