Physical Properties of PMMA Denture Base with Added Organoselenium as an Antifungal

Background/Objectives: The present study investigated the effects on the mechanical and physical properties of PMMA when organoselenium was incorporated into it as antifungal at different concentrations. Methods: 141 PMMA rectangle samples were fabricated using a heat compression packing technique and assigned to 3 experimental groups (47/group): 0% organoselenium (control), 0.5% organoselenium (0.5% SE), and 1% organoselenium (1% SE). Each sample was post-processed and stored in water. A three-point bend test was performed to assess elastic modulus and flexural stress. Scanning electron microscopy (SEM) was used to examine the exterior and interior surface topography. Data were analyzed using one-way ANOVA with Tukey’s multiple comparisons test. Results: The mean flexure stress for the 0% samples was statistically significantly higher than those of the 0.5% samples and the 1% samples (p < 0.001). The mean elastic modulus for the 0% group was statistically significantly higher than those of the 0.5% group and the 1% group (p < 0.001). Under SEM, the 0.5% samples were smoother with fewer voids and irregularities. Conclusions: The incorporation of organoselenium into PMMA denture base negatively affected its physical and mechanical properties.