Increasing Infusion Times of Hyperpolarized [1‐ <scp> <sup>13</sup> C </scp> ]Pyruvate in a Mouse Brain Maintain Lactate Generation and Approach Pseudo‐Steady State Metabolism
Increased delivery times of hyperpolarized [1-<sup>13</sup>C]pyruvate dissolved in D<sub>2</sub>O approaches pseudo-steady state metabolism in vivo and allowing for the potential to cater new acquisition and reconstruction approaches for enhanced imaging.
Authors
- Paola Porcari (ORCID: https://orcid.org/0000-0002-1011-1762)
- Kayvan R. Keshari (ORCID: https://orcid.org/0000-0002-5181-8035)
- Thasin Peyear
- Vesselin Z. Miloushev (ORCID: https://orcid.org/0000-0002-1899-8791)
- Marjan Berishaj (ORCID: https://orcid.org/0009-0006-1872-6522)
- Saket Patel (ORCID: https://orcid.org/0000-0001-7306-3326)
Institutions
- Memorial Sloan Kettering Cancer Center (US)
- Cornell University (US)
Publication Details
- Journal
- Magnetic Resonance in Medicine
- Published
- 2025-11-11
- DOI
- https://doi.org/10.1002/mrm.70175
- Primary Topic
- Advanced NMR Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Memorial Sloan-Kettering Cancer Center
- Peter Michael Foundation
- Thompson Family Foundation
- National Institutes of Health