Unravelling the complex inflammatory landscape of COVID-19 infection: a pathway to biomarkers identification in infection-associated delirium in the ICU
Our findings demonstrate a distinct immune profile linked to ICU delirium and illustrate how ML can enhance biomarker discovery. Further prospective validation may refine these markers and guide precision-targeted interventions for mitigating delirium in critically ill populations.
Authors
- Andrea O. Rossetti (ORCID: https://orcid.org/0000-0002-7878-172X)
- Raphaël Bernard‐Valnet (ORCID: https://orcid.org/0000-0001-7447-344X)
- Craig Fenwick (ORCID: https://orcid.org/0000-0002-9435-0110)
- Nawfel Ben‐Hamouda (ORCID: https://orcid.org/0000-0003-4428-5223)
- Tristan Born (ORCID: https://orcid.org/0000-0003-0932-5955)
- Matthieu Perreau (ORCID: https://orcid.org/0000-0003-2110-2244)
- Pierre‐Paul Axisa (ORCID: https://orcid.org/0000-0003-1446-3922)
- Andréa de Vasconcelos Freitas Pinto (ORCID: https://orcid.org/0000-0002-9306-418X)
- Jean‐Daniel Chiche (ORCID: https://orcid.org/0000-0002-6433-6254)
- Renaud Du Pasquier (ORCID: https://orcid.org/0000-0002-2786-3434)
Institutions
- Centre National de la Recherche Scientifique (FR)
- Université Toulouse III - Paul Sabatier (FR)
- Inserm (FR)
- Centre Hospitalier Universitaire Vaudois (CH)
- ETH Zurich (CH)
- Centre de Recherches en Cancérologie de Toulouse (FR)
Publication Details
- Journal
- Intensive Care Medicine Experimental
- Published
- 2025-11-12
- DOI
- https://doi.org/10.1186/s40635-025-00825-w
- Primary Topic
- Intensive Care Unit Cognitive Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Université de Lausanne