Analysis of the clinical characteristics of bone metastases after pheochromocytoma/paraganglioma surgery

PPGLs exhibit a pronounced tropism for bone, metastasizing to the skeletal system with higher frequency than to organs like the liver or lungs. These bone metastases are frequently associated with skeletal complications. SDHB mutation is a risk factor for bone metastases in PPGLs. It is crucial to emphasize genetic detection and postoperative follow-up examinations in patients with PPGLs.

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Publication Details

Journal
Frontiers in Endocrinology
Published
2025-11-11
DOI
https://doi.org/10.3389/fendo.2025.1657202
Primary Topic
Adrenal and Paraganglionic Tumors
Type
article
Field-Weighted Citation Impact
0.00
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article

Analysis of the clinical characteristics of bone metastases after pheochromocytoma/paraganglioma surgery

L Y Li, Hongbo Gao, Xinxin Zhu, Yujun Shao
Frontiers in Endocrinology
Adrenal and Paraganglionic Tumors
article

Analysis of the clinical characteristics of bone metastases after pheochromocytoma/paraganglioma surgery

L Y Li, Hongbo Gao, Xinxin Zhu, Yujun Shao
article en

Abstract

PPGLs exhibit a pronounced tropism for bone, metastasizing to the skeletal system with higher frequency than to organs like the liver or lungs. These bone metastases are frequently associated with skeletal complications. SDHB mutation is a risk factor for bone metastases in PPGLs. It is crucial to emphasize genetic detection and postoperative follow-up examinations in patients with PPGLs.

Frontiers in EndocrinologyVol. 16
China National Nuclear Corporation (CN), Aerospace Center Hospital (CN), Chemical Industry Press (CN)
Openalex Percentile: Top 48%
Adrenal and Paraganglionic Tumors
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