Integrated genomic and structural dissection of melanism in Indian leopard (Panthera pardus fusca)
Our results support the conclusion that the p.C117F mutation significantly contributes to melanism in Indian leopards, shedding new light on this trait's molecular underpinnings and evolutionary history. This study identifies the p.C117F mutation as a key driver of melanism in leopards of the Indian subcontinent, providing mechanistic insight into the evolution of complex phenotypes in non-model species.
Authors
- Mukesh Kumar Thakur (ORCID: https://orcid.org/0000-0003-2609-7579)
- Sweta Nidhi
- Malay Shukla (ORCID: https://orcid.org/0000-0002-7239-5537)
- Avijit Ghosh (ORCID: https://orcid.org/0000-0001-8311-8650)
- Satish Kumar (ORCID: https://orcid.org/0000-0002-2993-3694)
- Abhishek Singh (ORCID: https://orcid.org/0000-0002-2202-3719)
- Paresh C. Porob (ORCID: https://orcid.org/0009-0000-8266-3657)
Institutions
- National Forensic Sciences University (IN)
- Zoological Survey of India (IN)
- Goa University (IN)
- Amity University (IN)
- National Centre for Biological Sciences (IN)
- Goa Medical College (IN)
- National Law Institute University (IN)
- Voluntary Health Association of Goa (IN)
Publication Details
- Journal
- BMC Genomics
- Published
- 2025-11-11
- DOI
- https://doi.org/10.1186/s12864-025-12227-z
- Primary Topic
- melanin and skin pigmentation
- Type
- article
- Field-Weighted Citation Impact
- 0.00