Early lactate kinetics predicts survival and neurological outcomes after out-of-hospital cardiac arrest: a retrospective cohort study
Serial lactate trajectories within the first 24 h after ROSC were strongly associated with survival and neurological recovery in OHCA patients. Modeling lactate as a continuous dynamic biomarker using LMM captured prognostic information beyond single time points and may help guide individualized post-resuscitation management.
Authors
- Hung-Hsin Huang (ORCID: https://orcid.org/0000-0002-1981-0439)
- Hong-Mo Shih (ORCID: https://orcid.org/0000-0001-7732-3594)
- Yen-Wei Chiu (ORCID: https://orcid.org/0000-0001-8661-6575)
- Shaohua Yu (ORCID: https://orcid.org/0000-0003-1072-7935)
- Chin-Han Lin (ORCID: https://orcid.org/0000-0001-5592-1788)
- Shuangyu Lu
Institutions
- China Medical University (TW)
- China Medical University Hospital (TW)
- Taichung Hospital (TW)
Publication Details
- Journal
- BMC Emergency Medicine
- Published
- 2025-11-11
- DOI
- https://doi.org/10.1186/s12873-025-01388-5
- Primary Topic
- Cardiac Arrest and Resuscitation
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- China Medical University Hospital
- China Medical University
- Division of Materials Research