Comparison of ERS/ATS guidelines across versions: differences in the application of bronchodilator responsiveness criteria in pediatric asthma by age subgroups (2005 vs 2021)

The kappa test showed that the results of 2005BDR and 2021BDR were consistent, but there were differences between the inconsistent groups. Z-FEV1 is an independent factor affecting the inconsistent results, so baseline data is the main reason for the inconsistent results of the two methods. The 2021BDR standard may reduce the influence of baseline lung function when determining the results. The positive rate obtained based on the two evaluation criteria maintained the same trend with the degree of airflow obstruction. All showed a weak positive correlation.