Cytological Diagnosis of Primary Effusion Lymphoma in the Uncommon Clinical Setting of an <scp>HIV</scp> ‐Negative Patient With End‐Stage Renal Disease: A Case Report and Literature Review

Primary effusion lymphoma (PEL) represents a small proportion of non-Hodgkin lymphomas. It typically manifests as a serous effusion in HIV-positive patients and is associated with Kaposi sarcoma-associated herpesvirus/human herpesvirus 8 (KSHV/HHV8). We, herein, describe a case of PEL in an 84-year-old male, with HIV-negative status and on haemodialysis (HD) for end-stage renal disease (ESRD). This report emphasizes the significance of cytological examination of effusions, especially in those with no tumour mass, who present with persistent or recurrent effusions.

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Journal
Cytopathology
Published
2025-11-11
DOI
https://doi.org/10.1111/cyt.70038
Primary Topic
Viral-associated cancers and disorders
Type
article
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article

Cytological Diagnosis of Primary Effusion Lymphoma in the Uncommon Clinical Setting of an HIV ‐Negative Patient With End‐Stage Renal Disease: A Case Report and Literature Review

Anthony Maddox, Mohamed Sulaiman
Cytopathology
Viral-associated cancers and disorders
article

Cytological Diagnosis of Primary Effusion Lymphoma in the Uncommon Clinical Setting of an HIV ‐Negative Patient With End‐Stage Renal Disease: A Case Report and Literature Review

Anthony Maddox, Mohamed Sulaiman
article en

Abstract

Primary effusion lymphoma (PEL) represents a small proportion of non-Hodgkin lymphomas. It typically manifests as a serous effusion in HIV-positive patients and is associated with Kaposi sarcoma-associated herpesvirus/human herpesvirus 8 (KSHV/HHV8). We, herein, describe a case of PEL in an 84-year-old male, with HIV-negative status and on haemodialysis (HD) for end-stage renal disease (ESRD). This report emphasizes the significance of cytological examination of effusions, especially in those with no tumour mass, who present with persistent or recurrent effusions.

CytopathologyVol. 37(2)
Hemel Hempstead Hospital (GB)
Openalex Percentile: Top 54%
Viral-associated cancers and disorders
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