Spreading depolarization is followed by seizure-like activation of the hippocampus: potential mechanism of migraine-aura triggered seizures
This is the first experimental evidence that SD can trigger seizure-like activity in particular regions of awake non-epileptic brain. We suggest that the phenomenon may be relevant to mechanisms of migraine-aura triggered seizures (migralepsy).
Authors
- И. В. Павлова (ORCID: https://orcid.org/0000-0001-8898-6676)
- Maria P. Smirnova (ORCID: https://orcid.org/0000-0002-6668-958X)
- Lyudmila V. Vinogradova (ORCID: https://orcid.org/0000-0003-0336-606X)
Institutions
- Institute of Higher Nervous Activity and Neurophysiology (RU)
Publication Details
- Journal
- The Journal of Headache and Pain
- Published
- 2025-11-11
- DOI
- https://doi.org/10.1186/s10194-025-02199-6
- Citations
- 1
- Primary Topic
- Migraine and Headache Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.47
Funders
- Russian Science Foundation