High prevalence and multifactorial risks of sarcopenia in knee osteoarthritis: a systematic review and meta-analysis
Sarcopenia and sarcopenic obesity are highly prevalent in patients with KOA and are significantly associated with disease severity, gender, geographic region, comorbidities, and lifestyle factors. These findings highlight the clinical importance of assessing sarcopenia in KOA management. Early screening and timely interventions may improve patient outcomes and quality of life.
Authors
- Tianyou Yang (ORCID: https://orcid.org/0000-0001-9140-3806)
- Tao Liu (ORCID: https://orcid.org/0000-0001-6951-1165)
- Tian-Xin Chen (ORCID: https://orcid.org/0000-0002-9663-6294)
- Zhilong Zhang (ORCID: https://orcid.org/0009-0009-9307-8440)
- Sheng Cheng
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- People's Hospital of Kaizhou District (CN)
- China Academy of Chinese Medical Sciences (CN)
- First People's Hospital of Chongqing (CN)
Publication Details
- Journal
- Journal of Orthopaedic Surgery and Research
- Published
- 2025-11-11
- DOI
- https://doi.org/10.1186/s13018-025-06391-x
- Citations
- 1
- Primary Topic
- Nutrition and Health in Aging
- Type
- article
- Field-Weighted Citation Impact
- 1.16