Successfully treated a rare case of amebic mediastinal abscess complicated by a pseudoaneurysm of the right subclavian artery

Amebiasis, caused by Entamoeba histolytica, is an intestinal disease that can lead to severe complications such as ulcers and abscesses. While the intestine is most commonly affected, extraintestinal involvement is also possible. However, mediastinal amebiasis remains rare. This case report details a patient with amebiasis who developed an amebic mediastinal abscess, which subsequently ruptured into the pleural cavity, resulting in bilateral empyema and a pseudoaneurysm of the right subclavian artery. Treatment was promptly initiated with metronidazole, alongside closed pleural drainage. Additionally, endovascular stent placement was performed to address the right subclavian artery pseudoaneurysm. The patient was discharged in good health on the 37th postoperative day. The treatment approach described offers valuable clinical insights for frontline healthcare providers.

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Publication Details

Journal
BMC Infectious Diseases
Published
2025-11-11
DOI
https://doi.org/10.1186/s12879-025-11971-7
Primary Topic
Amoebic Infections and Treatments
Type
article
Field-Weighted Citation Impact
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article

Successfully treated a rare case of amebic mediastinal abscess complicated by a pseudoaneurysm of the right subclavian artery

Ye Yuan, Qun-Xian Zhang, Qiang Guo, Hua Liu et al.
BMC Infectious Diseases
Amoebic Infections and Treatments
article

Successfully treated a rare case of amebic mediastinal abscess complicated by a pseudoaneurysm of the right subclavian artery

Ye Yuan, Qun-Xian Zhang, Qiang Guo, Hua Liu, Tao Liu, Yang Ye, Min Zeng
article en

Abstract

Amebiasis, caused by Entamoeba histolytica, is an intestinal disease that can lead to severe complications such as ulcers and abscesses. While the intestine is most commonly affected, extraintestinal involvement is also possible. However, mediastinal amebiasis remains rare. This case report details a patient with amebiasis who developed an amebic mediastinal abscess, which subsequently ruptured into the pleural cavity, resulting in bilateral empyema and a pseudoaneurysm of the right subclavian artery. Treatment was promptly initiated with metronidazole, alongside closed pleural drainage. Additionally, endovascular stent placement was performed to address the right subclavian artery pseudoaneurysm. The patient was discharged in good health on the 37th postoperative day. The treatment approach described offers valuable clinical insights for frontline healthcare providers.

BMC Infectious DiseasesVol. 25(1)
Hubei University of Medicine (CN), Taihe Hospital (CN), People's Hospital of Shiyan (CN)
Openalex Percentile: Top 61%
Amoebic Infections and Treatments
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