The impact of cytological preparation techniques on RNA quality: A comparative study on smear samples
Among cytology smear techniques, MGG provided the best RNA preservation, PAP the worst, and air-dried slides yielded inconsistent results. These findings highlight the critical role of smear preparation in preserving RNA for molecular testing, especially RNA-based next-generation sequencing.
Authors
- İbrahim Kulaç (ORCID: https://orcid.org/0000-0003-2003-7567)
- Ayşe Hümeyra Dur Karasayar (ORCID: https://orcid.org/0000-0003-3820-0430)
- Makbule Aydın (ORCID: https://orcid.org/0000-0002-4541-793X)
- Zeynep Seçil Satilmis (ORCID: https://orcid.org/0009-0003-8005-5553)
- Gulsum Caylak (ORCID: https://orcid.org/0009-0000-9995-6608)
- Elif Sevin Sanioglu (ORCID: https://orcid.org/0009-0001-5063-8075)
Institutions
- Koç University (TR)
- Central Bank of the Republic of Turkey (TR)
- Istanbul Metropolitan Municipality (TR)
Publication Details
- Journal
- Cancer Cytopathology
- Published
- 2025-11-11
- DOI
- https://doi.org/10.1002/cncy.70060
- Primary Topic
- Molecular Biology Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00