Active limb-protection in type A aortic dissection complicated by lower-extremity malperfusion

Lower extremity ischemia in acute type A aortic dissection is associated with severe complications, including amputation, acute kidney injury, and increased mortality. Timely restoration of blood flow is critical to balance the risks of delayed extremity reperfusion against those of postponed central aortic repair. We present a multidisciplinary approach involving early extremity reperfusion without delaying central aortic repair, thereby minimizing ischemia-reperfusion injury while ensuring definitive aortic management.

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Publication Details

Journal
Perfusion
Published
2025-11-11
DOI
https://doi.org/10.1177/02676591251397510
Primary Topic
Aortic Disease and Treatment Approaches
Type
article
Field-Weighted Citation Impact
0.00
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article

Active limb-protection in type A aortic dissection complicated by lower-extremity malperfusion

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Perfusion
Aortic Disease and Treatment Approaches
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Active limb-protection in type A aortic dissection complicated by lower-extremity malperfusion

Bobby Hiu Nam Chow, Jay D. Pal, Kirsten Dansey, Ioannis Dimarakis, Julia Glizevskaja, Shohei Yoshida, John A. Carey
article en

Abstract

Lower extremity ischemia in acute type A aortic dissection is associated with severe complications, including amputation, acute kidney injury, and increased mortality. Timely restoration of blood flow is critical to balance the risks of delayed extremity reperfusion against those of postponed central aortic repair. We present a multidisciplinary approach involving early extremity reperfusion without delaying central aortic repair, thereby minimizing ischemia-reperfusion injury while ensuring definitive aortic management.

Perfusion
University of Washington (US), University of Washington Medical Center (US), Manchester University NHS Foundation Trust (GB), Wythenshawe Hospital (GB)
Openalex Percentile: Top 52%
Aortic Disease and Treatment Approaches
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