REM sleep reduction leads to fear overgeneralization via negatively modulating prefrontal theta oscillations
These findings demonstrate the essential role of post-conditioning REM sleep, particularly its reliance on theta oscillations in the frontal lobe, in mitigating fear overgeneralization.
Authors
- Jie Shi (ORCID: https://orcid.org/0000-0001-6567-8160)
- Zhoulong Yu
- Tianye Jia (ORCID: https://orcid.org/0000-0001-5399-2953)
- Enyu Zheng
- Lin Lü (ORCID: https://orcid.org/0000-0003-0742-9072)
- Yang Guo (ORCID: https://orcid.org/0000-0003-1552-5128)
- Yan Sun
- Jianfeng Liu (ORCID: https://orcid.org/0000-0002-3464-6462)
- Le Shi (ORCID: https://orcid.org/0000-0003-4827-4003)
- Tianqi Di
- Wangyue Liu
Institutions
- Peking University (CN)
- Fudan University (CN)
- Shanghai Institute for Science of Science (CN)
- Ministry of Education (RO)
- Peking University Sixth Hospital (CN)
- Shanghai Center for Brain Science and Brain-Inspired Technology (CN)
- Wuhan University of Science and Technology (CN)
Publication Details
- Journal
- BMC Medicine
- Published
- 2025-11-11
- DOI
- https://doi.org/10.1186/s12916-025-04411-5
- Citations
- 1
- Primary Topic
- Sleep and Wakefulness Research
- Type
- article
- Field-Weighted Citation Impact
- 1.43
Funders
- National Natural Science Foundation of China
- Fudan University