Nonlinear association between high-density lipoprotein cholesterol and carotid atherosclerosis risk in patients with type 2 diabetes: a retrospective analysis from China
Our findings unveil an L-shaped correlation between HDL-C and CAS risk, with a distinct protective effect of HDL-C observed only below the inflection point. Our findings suggest the potential value of clinical trials aiming to elevate HDL-C as a therapeutic strategy for controlling CAS.
Authors
- Meiling Huang
- Changchun Cao (ORCID: https://orcid.org/0000-0003-1992-4257)
- Yi Zheng (ORCID: https://orcid.org/0000-0001-7089-6074)
- Haofei Hu (ORCID: https://orcid.org/0000-0001-6061-6796)
- Yong Han (ORCID: https://orcid.org/0000-0001-6149-3724)
- Fubing Zha (ORCID: https://orcid.org/0000-0002-5231-1973)
Institutions
- Shenzhen Sixth People's Hospital (CN)
- ShenZhen People’s Hospital (CN)
- Shenzhen Bao'an District People's Hospital (CN)
- Shenzhen Second People's Hospital (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2025-11-11
- DOI
- https://doi.org/10.1186/s40001-025-03284-x
- Citations
- 1
- Primary Topic
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Type
- article
- Field-Weighted Citation Impact
- 1.29
Funders
- Science, Technology and Innovation Commission of Shenzhen Municipality