Association between choroid plexus volume and cognitive function in older-age bipolar disorder
CP abnormalities are prominent in OABD, with larger CPV linked to greater cognitive impairment, suggesting that CP may serve as a potential therapeutic target for mitigating cognitive impairment and slowing disease progression in BD. Additionally, the cognitive performance in OABD was associated with GMV, CSV and TBV, further underscoring the role of structural brain abnormalities in cognitive impairment.
Authors
- Bin Guo (ORCID: https://orcid.org/0000-0001-7946-6740)
- Xiqin Liu (ORCID: https://orcid.org/0000-0001-5723-8392)
- Qiyong Gong (ORCID: https://orcid.org/0000-0002-5912-4871)
- Kun Qin (ORCID: https://orcid.org/0000-0003-1254-6388)
- Jian-Yu Li (ORCID: https://orcid.org/0009-0005-5702-9781)
- Ziqi Chen (ORCID: https://orcid.org/0000-0001-8699-3848)
- Lisha Zhang (ORCID: https://orcid.org/0000-0003-2082-5125)
Institutions
- Hubei University of Medicine (CN)
- Jimei University (CN)
- Xiamen University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Sichuan University (CN)
- First Affiliated Hospital of Xiamen University (CN)
- West China Hospital of Sichuan University (CN)
- Zhongshan Hospital of Xiamen University (CN)
Publication Details
- Journal
- BMC Psychiatry
- Published
- 2025-11-11
- DOI
- https://doi.org/10.1186/s12888-025-07506-8
- Primary Topic
- Bipolar Disorder and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Hubei Province