Use of Corticosteroids in Children with Bell’s Palsy: A Systematic Review and Meta-Analysis

<b>Importance</b>: Corticosteroids are recommended as first-line treatment for adults with acute Bell's palsy, but their role in children remains uncertain. <b>Objective:</b> To assess the effect of corticosteroid therapy on recovery rates in children with acute Bell's palsy. <b>Evidence Review</b>: PubMed, Scopus, and Cochrane Library were systematically searched from inception to April 2, 2025, for studies on corticosteroids for children with Bell's palsy. Odds ratios and risk ratios with 95% confidence intervals were pooled using R software (version 4.2.3). Risk of bias was assessed with RoB2 and ROBINS-I. <b>Findings</b>: Eleven studies were included, comprising 750 children, of whom 495 (66%) received corticosteroids. The analysis across final follow-ups showed no significant difference. Because follow-ups ranged from 1 to 24 months, 1, 3, and 6 months were used as key points to create comparable intervals. The following subgroups were analyzed for each interval: corticosteroid monotherapy and corticosteroids plus adjunctive therapy. Corticosteroid monotherapy was associated with higher complete recovery rates beyond 1 month and a lower risk of incomplete recovery after 6 months. <b>Conclusions and Relevance</b>: Corticosteroid monotherapy in children with acute Bell's palsy may improve recovery rates beyond the first month, supporting its implementation in treatment protocols.

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Publication Details

Journal
Facial Plastic Surgery & Aesthetic Medicine
Published
2025-11-12
DOI
https://doi.org/10.1177/26893614251394388
Primary Topic
Facial Nerve Paralysis Treatment and Research
Type
article
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article

Use of Corticosteroids in Children with Bell’s Palsy: A Systematic Review and Meta-Analysis

Javiér Gavilán, José Manuel Morales‐Puebla, Luis Lassaletta, Fabio Peralta et al.
Facial Plastic Surgery & Aesthetic Medicine
Facial Nerve Paralysis Treatment and Research
article

Use of Corticosteroids in Children with Bell’s Palsy: A Systematic Review and Meta-Analysis

Javiér Gavilán, José Manuel Morales‐Puebla, Luis Lassaletta, Fabio Peralta, Francis Evilda Miralda Matute, Roman Pati
article en

Abstract

<b>Importance</b>: Corticosteroids are recommended as first-line treatment for adults with acute Bell's palsy, but their role in children remains uncertain. <b>Objective:</b> To assess the effect of corticosteroid therapy on recovery rates in children with acute Bell's palsy. <b>Evidence Review</b>: PubMed, Scopus, and Cochrane Library were systematically searched from inception to April 2, 2025, for studies on corticosteroids for children with Bell's palsy. Odds ratios and risk ratios with 95% confidence intervals were pooled using R software (version 4.2.3). Risk of bias was assessed with RoB2 and ROBINS-I. <b>Findings</b>: Eleven studies were included, comprising 750 children, of whom 495 (66%) received corticosteroids. The analysis across final follow-ups showed no significant difference. Because follow-ups ranged from 1 to 24 months, 1, 3, and 6 months were used as key points to create comparable intervals. The following subgroups were analyzed for each interval: corticosteroid monotherapy and corticosteroids plus adjunctive therapy. Corticosteroid monotherapy was associated with higher complete recovery rates beyond 1 month and a lower risk of incomplete recovery after 6 months. <b>Conclusions and Relevance</b>: Corticosteroid monotherapy in children with acute Bell's palsy may improve recovery rates beyond the first month, supporting its implementation in treatment protocols.

Facial Plastic Surgery & Aesthetic Medicine
Washington University in St. Louis (US), Hospital Universitario La Paz (ES), Instituto de Salud Carlos III (ES), Centre for Biomedical Network Research on Rare Diseases (ES), Centro de Investigación Biomédica en Red (ES), Universidad Católica de Honduras Nuestra Señora Reina de la Paz (HN), Universidad Metropolitana de Honduras (HN), Universidad Peruana Unión (PE), Instituto de Investigación de Enfermedades Raras (ES)
Openalex Percentile: Top 53%
Facial Nerve Paralysis Treatment and Research
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