Use of Corticosteroids in Children with Bell’s Palsy: A Systematic Review and Meta-Analysis
<b>Importance</b>: Corticosteroids are recommended as first-line treatment for adults with acute Bell's palsy, but their role in children remains uncertain. <b>Objective:</b> To assess the effect of corticosteroid therapy on recovery rates in children with acute Bell's palsy. <b>Evidence Review</b>: PubMed, Scopus, and Cochrane Library were systematically searched from inception to April 2, 2025, for studies on corticosteroids for children with Bell's palsy. Odds ratios and risk ratios with 95% confidence intervals were pooled using R software (version 4.2.3). Risk of bias was assessed with RoB2 and ROBINS-I. <b>Findings</b>: Eleven studies were included, comprising 750 children, of whom 495 (66%) received corticosteroids. The analysis across final follow-ups showed no significant difference. Because follow-ups ranged from 1 to 24 months, 1, 3, and 6 months were used as key points to create comparable intervals. The following subgroups were analyzed for each interval: corticosteroid monotherapy and corticosteroids plus adjunctive therapy. Corticosteroid monotherapy was associated with higher complete recovery rates beyond 1 month and a lower risk of incomplete recovery after 6 months. <b>Conclusions and Relevance</b>: Corticosteroid monotherapy in children with acute Bell's palsy may improve recovery rates beyond the first month, supporting its implementation in treatment protocols.
Authors
- Javiér Gavilán (ORCID: https://orcid.org/0000-0002-9357-5932)
- José Manuel Morales‐Puebla (ORCID: https://orcid.org/0000-0003-3976-4019)
- Luis Lassaletta (ORCID: https://orcid.org/0000-0002-8260-4523)
- Fabio Peralta (ORCID: https://orcid.org/0009-0000-3469-5566)
- Francis Evilda Miralda Matute
- Roman Pati
Institutions
- Washington University in St. Louis (US)
- Hospital Universitario La Paz (ES)
- Instituto de Salud Carlos III (ES)
- Centre for Biomedical Network Research on Rare Diseases (ES)
- Centro de Investigación Biomédica en Red (ES)
- Universidad Católica de Honduras Nuestra Señora Reina de la Paz (HN)
- Universidad Metropolitana de Honduras (HN)
- Universidad Peruana Unión (PE)
- Instituto de Investigación de Enfermedades Raras (ES)
Publication Details
- Journal
- Facial Plastic Surgery & Aesthetic Medicine
- Published
- 2025-11-12
- DOI
- https://doi.org/10.1177/26893614251394388
- Primary Topic
- Facial Nerve Paralysis Treatment and Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00