Evaluation of the relation of CD133 expression measured by immunohistochemistry assay with the survival of the colorectal cancer patients: a retrospective cohort study
CD133 expression is significantly associated with high tumor grade and poor survival in Iranian CRC patients, but findings should be interpreted with caution, given the small cohort. Its evaluation could aid in identifying high-risk individuals and guiding personalized treatment strategies in larger confirmatory studies.
Authors
- Farzane Ahmadi (ORCID: https://orcid.org/0000-0001-8609-1860)
- Yekta Ghane (ORCID: https://orcid.org/0000-0002-7309-4066)
- Ahmad Jalilvand (ORCID: https://orcid.org/0000-0003-0945-0852)
- Maliheh Naghavi (ORCID: https://orcid.org/0000-0002-5177-5530)
- Ali Ezzatollahi Tanha (ORCID: https://orcid.org/0009-0004-5239-7967)
- Niloofar Nikkhahbahrami (ORCID: https://orcid.org/0009-0000-8814-4487)
- Keyvan Nikkhah Bahrami (ORCID: https://orcid.org/0009-0008-5959-6693)
Institutions
- Zanjan University of Medical Sciences (IR)
- Universität Hamburg (DE)
- Iran University of Medical Sciences (IR)
- University Medical Center Hamburg-Eppendorf (DE)
- Elbe Kliniken Stade-Buxtehude (DE)
- Tehran University of Medical Sciences (IR)
Publication Details
- Journal
- International Journal of Colorectal Disease
- Published
- 2025-11-12
- DOI
- https://doi.org/10.1007/s00384-025-05018-1
- Primary Topic
- Cancer Cells and Metastasis
- Type
- article
- Field-Weighted Citation Impact
- 0.00