Computational-experimental strategy identifies Co-upregulated biomarkers linking coronary heart disease and type 2 diabetes pathogenesis
This study establishes CPD, GGCT, SUZ12, and ZMYM2 as shared CHD/T2D diagnostic biomarkers. Their validated co-upregulation highlights their dual-disease diagnostic and therapeutic potential.
Authors
- Miao He (ORCID: https://orcid.org/0000-0002-9514-7384)
- Yu Cao (ORCID: https://orcid.org/0000-0003-1992-509X)
- Wei Li (ORCID: https://orcid.org/0000-0002-7530-4872)
- Yu Chen (ORCID: https://orcid.org/0009-0001-9657-197X)
- Dong‐Zhi Li (ORCID: https://orcid.org/0000-0002-4583-6800)
- Lihong Jiang (ORCID: https://orcid.org/0000-0002-5759-2903)
- Lifeng Ma
- Bingjun Che
Institutions
- Kunming University of Science and Technology (CN)
- Kunming Medical University (CN)
- Second Affiliated Hospital of Kunming Medical College (CN)
- First People's Hospital of Yunnan Province (CN)
- The First Hospital of Kunming (CN)
- First Affiliated Hospital of Kunming Medical University (CN)
Publication Details
- Journal
- Frontiers in Genetics
- Published
- 2025-11-11
- DOI
- https://doi.org/10.3389/fgene.2025.1673303
- Primary Topic
- Biomarkers in Disease Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Kunming Medical University