Endogenous nitric oxide synthase inhibitor asymmetric dimethylarginine ameliorates lipopolysaccharide-induced airway inflammation and bronchial hyperreactivity in mice
Exogenously applied ADMA may have protective effects in airway inflammation by limiting excessive nitric oxide (NO) production. Targeting the DDAH/ADMA/NOS pathway may provide a therapeutic approach for airway inflammation.
Authors
- Yasemin Karaman (ORCID: https://orcid.org/0000-0003-4491-1394)
- Turgut Emrah Bozkurt (ORCID: https://orcid.org/0000-0001-8650-176X)
- Sevgen Önder (ORCID: https://orcid.org/0000-0002-5523-0669)
- Yeşim Kaya Yaşar (ORCID: https://orcid.org/0000-0002-9938-3288)
- İnci Şahin-Erdemli
Institutions
- Karadeniz Technical University (TR)
- Hacettepe University (TR)
Publication Details
- Journal
- Journal of Pharmacy and Pharmacology
- Published
- 2025-11-11
- DOI
- https://doi.org/10.1093/jpp/rgaf112
- Citations
- 1
- Primary Topic
- Nitric Oxide and Endothelin Effects
- Type
- article
- Field-Weighted Citation Impact
- 1.16