Emerging approaches in the management of intracranial hemorrhage: ARISE II consensus recommendations
Despite advances in the fundamental understanding of the pathophysiology of intracranial hemorrhage (ICH), many issues related to ICH management remain understudied with discrepancies in management. Given the high disease severity and prevalence, consensus recommendations are urgently needed to guide further research and management strategies. Thus, a group of clinical experts, industry leaders, and government representatives was assembled to examine emerging approaches in ICH management and their future impact on patient care. The timing of intervention within 24 hours and the role of minimally invasive evacuation, particularly for basal ganglia hemorrhage locations, were identified as key research focuses to guide future trial design. Mobile stroke units and artificial intelligence (AI) are promising technologies that streamline preoperative and triaging workflows and improve time to intervention. Efforts to further develop surgical technologies will be crucial to improve ICH visualization and evacuation. Further research, industry collaboration, and investment are needed to advance treatment frontiers and catalyze ICH research.
Authors
- Juhana Frösén (ORCID: https://orcid.org/0000-0003-4677-950X)
- Demetrius K. Lopes (ORCID: https://orcid.org/0000-0002-6280-0113)
- Ricardó A. Hanel (ORCID: https://orcid.org/0000-0001-7195-5806)
- Italo Linfante (ORCID: https://orcid.org/0000-0001-8973-4294)
- David S. Liebeskind (ORCID: https://orcid.org/0000-0002-5109-8736)
- Daniel Strbian (ORCID: https://orcid.org/0000-0001-9095-2344)
- J Mocco (ORCID: https://orcid.org/0000-0001-5489-2524)
- Gustavo Pradilla (ORCID: https://orcid.org/0000-0002-3661-3269)
- Christopher P. Kellner (ORCID: https://orcid.org/0000-0003-4604-8205)
- David J. Fiorella (ORCID: https://orcid.org/0000-0002-2677-8780)
- Edgar Andres Samaniego (ORCID: https://orcid.org/0000-0003-2764-2268)
- Adam S Arthur (ORCID: https://orcid.org/0000-0002-1536-1613)
- Philipp Taussky (ORCID: https://orcid.org/0000-0001-9247-0146)
- Jan‐Karl Burkhardt (ORCID: https://orcid.org/0000-0002-3726-4048)
- Ahmed Kashkoush (ORCID: https://orcid.org/0000-0002-2045-972X)
- Ajay K. Wakhloo (ORCID: https://orcid.org/0000-0003-4355-2107)
- Gabor G. Toth (ORCID: https://orcid.org/0000-0002-3646-3635)
- Brian T. Jankowitz (ORCID: https://orcid.org/0000-0001-9306-0763)
- Marc Fisher
- Mark Bain
- Raul G. Nogueira
Institutions
- Tufts Medical Center (US)
- Baptist Hospital of Miami (US)
- Beth Israel Deaconess Medical Center (US)
- Cleveland Clinic (US)
- Mount Sinai Health System (US)
- University of Helsinki (FI)
- Emory University (US)
- University of Tennessee Health Science Center (US)
- UCLA Health (US)
- University of Iowa Hospitals and Clinics (US)
- NYU Langone Health (US)
- Advocate Health Care (US)
- Baptist Health South Florida (US)
- Semmes Murphey Foundation (US)
- Pirkanmaa Hospital District (FI)
- Tampere University Hospital (FI)
- Baptist Medical Center Jacksonville (US)
- Tampere University (FI)
- Stony Brook University (US)
- University of Pennsylvania (US)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- Journal of NeuroInterventional Surgery
- Published
- 2025-11-11
- DOI
- https://doi.org/10.1136/jnis-2025-023855
- Primary Topic
- Intracerebral and Subarachnoid Hemorrhage Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00