Protective association of renin‐angiotensin system inhibitor use with skeletal muscle wasting in diabetic heart failure
RASI use was associated with significantly lower muscle wasting in HF patients with DM, particularly those with lower 3-Me-His levels. These findings suggest a potential therapeutic window and warrant prospective investigation.
Authors
- Hidemichi Kouzu (ORCID: https://orcid.org/0000-0001-7815-1464)
- Nobutaka Nagano
- Ryo Numazawa (ORCID: https://orcid.org/0009-0002-7238-1589)
- Satoshi Katano (ORCID: https://orcid.org/0000-0002-2562-1685)
- Ryohei Nagaoka (ORCID: https://orcid.org/0009-0002-0740-8677)
- Toshiyuki Yano (ORCID: https://orcid.org/0000-0001-9655-3985)
- Takefumi Fujito (ORCID: https://orcid.org/0000-0001-8224-3767)
- Wataru Kawaharata
- Hiroki Aida (ORCID: https://orcid.org/0009-0007-2615-6010)
- Katsuhiko Ohori
Institutions
- Sapporo Medical University (JP)
- Sapporo Medical University Hospital (JP)
Publication Details
- Journal
- Journal of Diabetes Investigation
- Published
- 2025-11-11
- DOI
- https://doi.org/10.1111/jdi.70186
- Primary Topic
- Cardiovascular and exercise physiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Japan Society for the Promotion of Science