Intravenous Liposomal Amphotericin as an Adjunct to Fluconazole in Pediatric Patients With Central Nervous System Coccidioidomycosis: A Single-Center Case Series
Our institutional experience with IV L-AmB in combination with fluconazole for the initial management of pediatric CNS coccidioidomycosis suggests that +IV L-AmB may help reduce disease progression and improve symptom resolution with mild and transient side effects, although the findings of this case series should be interpreted cautiously due to the small cohort size, limited generalizability, and potential confounding factors.
Authors
- Kajal Maran (ORCID: https://orcid.org/0000-0001-7619-5893)
- Aslam Khan (ORCID: https://orcid.org/0000-0003-4735-2700)
- Sharon Chen (ORCID: https://orcid.org/0000-0002-3705-258X)
- R. M. Adams
Institutions
- Palo Alto University (US)
- Stanford Medicine (US)
- Stanford University (US)
Publication Details
- Journal
- Journal of the Pediatric Infectious Diseases Society
- Published
- 2025-11-10
- DOI
- https://doi.org/10.1093/jpids/piaf103
- Primary Topic
- Fungal Infections and Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00