Intravenous Liposomal Amphotericin as an Adjunct to Fluconazole in Pediatric Patients With Central Nervous System Coccidioidomycosis: A Single-Center Case Series

Our institutional experience with IV L-AmB in combination with fluconazole for the initial management of pediatric CNS coccidioidomycosis suggests that +IV L-AmB may help reduce disease progression and improve symptom resolution with mild and transient side effects, although the findings of this case series should be interpreted cautiously due to the small cohort size, limited generalizability, and potential confounding factors.

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Publication Details

Journal
Journal of the Pediatric Infectious Diseases Society
Published
2025-11-10
DOI
https://doi.org/10.1093/jpids/piaf103
Primary Topic
Fungal Infections and Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Intravenous Liposomal Amphotericin as an Adjunct to Fluconazole in Pediatric Patients With Central Nervous System Coccidioidomycosis: A Single-Center Case Series

Kajal Maran, Aslam Khan, Sharon Chen, R. M. Adams
Journal of the Pediatric Infectious Diseases Society
Fungal Infections and Studies
article

Intravenous Liposomal Amphotericin as an Adjunct to Fluconazole in Pediatric Patients With Central Nervous System Coccidioidomycosis: A Single-Center Case Series

Kajal Maran, Aslam Khan, Sharon Chen, R. M. Adams
article en

Abstract

Our institutional experience with IV L-AmB in combination with fluconazole for the initial management of pediatric CNS coccidioidomycosis suggests that +IV L-AmB may help reduce disease progression and improve symptom resolution with mild and transient side effects, although the findings of this case series should be interpreted cautiously due to the small cohort size, limited generalizability, and potential confounding factors.

Journal of the Pediatric Infectious Diseases SocietyVol. 14(12)
Palo Alto University (US), Stanford Medicine (US), Stanford University (US)
Openalex Percentile: Top 56%
Fungal Infections and Studies
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