Predictors of Kyphoplasty Failures Requiring Surgical Stabilization in Patients With Cancer With Pathological Vertebral Body Fractures
Kyphoplasty failure in metastatic VCFs is associated with specific radiographic markers of spinal instability. Patients with spinal instability neoplastic score ≥11, posterior-element involvement, canal compromise, and significant kyphosis may benefit from up-front surgical stabilization with pedicle screws, particularly for patients with anticipated long-term survival.
Authors
- F. Cornélis (ORCID: https://orcid.org/0000-0002-1058-0884)
- Eric Lis (ORCID: https://orcid.org/0000-0002-4138-3867)
- Rabih Bou Nassif (ORCID: https://orcid.org/0000-0002-8789-8428)
- Anne S. Reiner (ORCID: https://orcid.org/0000-0002-1258-6112)
- Graham Winston (ORCID: https://orcid.org/0000-0002-3878-992X)
- Vikram Chakravarthy (ORCID: https://orcid.org/0000-0003-0081-6571)
- Ori Barzilai (ORCID: https://orcid.org/0000-0002-4037-8716)
- Justiss Kallos
- Mark H. Bilsky (ORCID: https://orcid.org/0000-0001-6091-0709)
- Ryan Khanna (ORCID: https://orcid.org/0000-0002-6345-200X)
- W. Christopher Newman
Institutions
- Memorial Sloan Kettering Cancer Center (US)
Publication Details
- Journal
- Neurosurgery
- Published
- 2025-11-11
- DOI
- https://doi.org/10.1227/neu.0000000000003846
- Primary Topic
- Spinal Fractures and Fixation Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00