The Coexistence of Diabetes Mellitus and Low Fecal Elastase Is Associated With Increased Pancreatic Cancer Risk: A Retrospective, Real-world Cohort Study
The coexistence of low fecal elastase and DM amplifies the risk of pancreatic ductal adenocarcinoma in our cohort of patients. These results suggest that fecal elastase values may be used to enrich the diabetic population for future PDAC risk stratification, though more studies are needed to validate these findings.
Authors
- Osayande Osagiede (ORCID: https://orcid.org/0000-0003-0799-0142)
- Chukwuemeka E. Ogbu (ORCID: https://orcid.org/0000-0002-9958-8478)
- Philip N. Okafor (ORCID: https://orcid.org/0000-0003-1695-7491)
- Yichen Wang (ORCID: https://orcid.org/0000-0003-0723-5913)
- Oyedotun Babajide (ORCID: https://orcid.org/0000-0002-1800-5665)
- Chukwunonso Ezeani (ORCID: https://orcid.org/0009-0004-6421-630X)
- Lekhya Kollu
Institutions
- New York City Health and Hospitals Corporation (US)
- New York Medical College (US)
- Metropolitan Hospital Center (US)
- Hospital of the University of Pennsylvania (US)
- Jacksonville College (US)
- Health First (US)
- Baton Rouge General (US)
- Cape Fear Valley Health System (US)
- Cape Fear Valley Medical Center (US)
- Mayo Clinic in Florida (US)
- Temple University (US)
Publication Details
- Journal
- Pancreas
- Published
- 2025-11-10
- DOI
- https://doi.org/10.1097/mpa.0000000000002592
- Primary Topic
- Pancreatitis Pathology and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00