Genome assembly of Megasphaera elsdenii CH4, a potential probiotic bacterium isolated from the rumen sample of Holstein dairy cow

Here, we describe the genome sequence of M. elsdenii isolate CH4, one of the most promising probiotic candidates, commonly administered as a direct-fed microbe supplement to ruminant animals. Sequencing reads from M. elsdenii produced approximately 5.6 Mb. The assembly generated a draft genome size of 2.5 Mb, consisting of 27 contigs, with an N50 of 102.8 KB. Examination of the genome completeness and contamination was assessed using CheckM v1.0.18 and reported as 93.57 and 4.34%, respectively. The draft genome sequence will allow improved genomic comparisons among the probiotic strains of the genus Megasphaera, particularly with the aim of improving our knowledge of their animal-probiotic interactions as well as their population biology.