Citrulline-enhanced chicken resistance to <i>Salmonella Enteritidis</i> infection via urea cycle modulation and nitric oxide production
Chickens respond to <i>Salmonella</i> infection by adjusting the metabolic state of their bodies. Citrulline can enhance the phagocytic ability of phagocytes by strengthening the urea cycle. <i>In vitro</i> clinical trials have revealed that citrulline can increase the survival rate of chickens after <i>Salmonella</i> infection.
Authors
- Ming Jiang (ORCID: https://orcid.org/0000-0002-8935-3886)
- Minmin Cai (ORCID: https://orcid.org/0000-0002-9613-7778)
- Chunlin Xie
- Pengzhi Hu (ORCID: https://orcid.org/0009-0006-0531-5580)
- Jie Ma (ORCID: https://orcid.org/0000-0003-1865-7679)
- Weimin Li
- Jianmin Zhang (ORCID: https://orcid.org/0000-0002-7713-2015)
- Jian Ji (ORCID: https://orcid.org/0000-0003-1175-7730)
- Wei Luo (ORCID: https://orcid.org/0000-0003-3938-5043)
- Chu-xiao Lin
Institutions
- South China Agricultural University (CN)
- Hunan Normal University (CN)
- Guangdong Academy of Agricultural Sciences (CN)
- China Agricultural University (CN)
Publication Details
- Journal
- Microbiology Spectrum
- Published
- 2025-11-11
- DOI
- https://doi.org/10.1128/spectrum.01546-25
- Citations
- 1
- Primary Topic
- Animal Nutrition and Physiology
- Type
- article
- Field-Weighted Citation Impact
- 1.19