MAFF drives pancreatic cancer progression through AKR1C1-mediated inhibition of ferroptosis
Our findings demonstrate that MAFF promotes tumorigenesis by suppressing ferroptosis and nominates MAFF as a promising therapeutic target for pancreatic cancer.
Authors
- Qiang She (ORCID: https://orcid.org/0000-0001-8861-2674)
- Xin Jiang (ORCID: https://orcid.org/0000-0003-2670-3188)
- Xuyu Chen (ORCID: https://orcid.org/0000-0002-6469-2320)
- Yanbing Ding (ORCID: https://orcid.org/0000-0002-0689-2199)
- Jean Xia
- Min Zhang (ORCID: https://orcid.org/0000-0002-4863-9431)
- Yuanyuan Chen (ORCID: https://orcid.org/0000-0001-5435-3248)
- Yaoyao Li (ORCID: https://orcid.org/0000-0002-8762-9615)
- Ben‐Gang Zhou
- Aiping Zhang (ORCID: https://orcid.org/0009-0000-9969-9437)
Institutions
- Yangzhou University (CN)
Publication Details
- Journal
- QJM
- Published
- 2025-11-06
- DOI
- https://doi.org/10.1093/qjmed/hcaf272
- Primary Topic
- Aldose Reductase and Taurine
- Type
- article
- Field-Weighted Citation Impact
- 0.00