Baseline neutrophil-to-lymphocyte ratio predicts drug retention of IL-6 inhibitors and JAK inhibitors in RA: the ANSWER cohort study
In patients with elevated baseline NLR values, aIL-6R and JAKi may offer superior drug retention compared with TNFi when initiating b/tsDMARD therapy.
Authors
- Kazuo Fukumoto (ORCID: https://orcid.org/0000-0002-8576-5816)
- Masao Katsushima (ORCID: https://orcid.org/0009-0007-0033-1757)
- Kosuke Ebina (ORCID: https://orcid.org/0000-0002-2426-1024)
- Motomu Hashimoto (ORCID: https://orcid.org/0000-0002-9241-060X)
- Tohru Takeuchi (ORCID: https://orcid.org/0000-0002-0065-929X)
- Yuji Nozaki (ORCID: https://orcid.org/0000-0003-2810-1519)
- Tadashi Okano (ORCID: https://orcid.org/0000-0002-8849-9824)
- Tetsu Itami (ORCID: https://orcid.org/0009-0000-9991-4176)
- Ayaka Yoshikawa (ORCID: https://orcid.org/0000-0002-1927-1295)
- Hidehiko Makino
- Yuhei Fujisawa (ORCID: https://orcid.org/0000-0002-1718-0752)
- Yonsu Son (ORCID: https://orcid.org/0000-0001-7244-7715)
- Shinsuke Yamada (ORCID: https://orcid.org/0000-0002-8433-9065)
- Ryu Watanabe (ORCID: https://orcid.org/0000-0002-1089-5296)
- Mai Yamashita (ORCID: https://orcid.org/0000-0003-0590-6584)
- Wataru Yamamoto (ORCID: https://orcid.org/0000-0003-0574-014X)
- H. Yamada (ORCID: https://orcid.org/0000-0002-8090-6755)
- Tsutomu TOGASHI (ORCID: https://orcid.org/0009-0001-0287-3660)
- Akira Onishi
- Kosaku Murakami (ORCID: https://orcid.org/0000-0001-5981-4648)
- Yuya Yano
Institutions
- Kansai Medical University (JP)
- Kyoto University (JP)
- Osaka City University (JP)
- Kurashiki Central Hospital (JP)
- Osaka Metropolitan University (JP)
- Kobe University (JP)
- Osaka University of Pharmaceutical Sciences (JP)
- Kindai University (JP)
- The University of Osaka (JP)
Publication Details
- Journal
- Lara D. Veeken
- Published
- 2025-11-08
- DOI
- https://doi.org/10.1093/rheumatology/keaf602
- Primary Topic
- Rheumatoid Arthritis Research and Therapies
- Type
- article
- Field-Weighted Citation Impact
- 0.00