Clinical features and chronology of clinical manifestations in Behçet’s disease: A cohort of 2615 patients

Our findings highlight substantial temporal heterogeneity in BD symptom progression. While oral ulcers appear early, genital ulcers and skin manifestations tend to develop later, and ocular and vascular lesions exhibit the longest delay. The chronology of symptom onset is significantly influenced by age, sex, HLA-B5/B51 status, and initial presenting symptom. These findings underscore the importance of long-term follow-up in BD management.

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Publication Details

Journal
Reumatologia/Rheumatology
Published
2025-11-11
DOI
https://doi.org/10.5114/reum/202818
Primary Topic
Ocular Diseases and Behçet’s Syndrome
Type
article
Field-Weighted Citation Impact
0.00

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article

Clinical features and chronology of clinical manifestations in Behçet’s disease: A cohort of 2615 patients

Azarakhsh Baghdadi, Shokufe Sadeghi, Farhad Shahram, Fereydoun Davatchi et al.
Reumatologia/Rheumatology
Ocular Diseases and Behçet’s Syndrome
article

Clinical features and chronology of clinical manifestations in Behçet’s disease: A cohort of 2615 patients

Azarakhsh Baghdadi, Shokufe Sadeghi, Farhad Shahram, Fereydoun Davatchi, Mohammad Nejadhosseinian, Seyedeh Tahereh Faezi, Majid Alikhani, Massoomeh Akhlaghi, Gilava Hedayati Emam
article en

Abstract

Our findings highlight substantial temporal heterogeneity in BD symptom progression. While oral ulcers appear early, genital ulcers and skin manifestations tend to develop later, and ocular and vascular lesions exhibit the longest delay. The chronology of symptom onset is significantly influenced by age, sex, HLA-B5/B51 status, and initial presenting symptom. These findings underscore the importance of long-term follow-up in BD management.

Reumatologia/RheumatologyVol. 63(5)
Tehran University of Medical Sciences (IR)
Tehran University of Medical Sciences and Health Services
Openalex Percentile: Top 52%
Ocular Diseases and Behçet’s Syndrome
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Clinical features and chronology of clinical manifestations in Behçet’s disease: A cohort of 2615 patients — Azarakhsh Baghdadi, Shokufe Sadeghi, et al. · Reumatologia/Rheumatology (2025) | TGRS Research Map | TGRS