The cuproptosis-related gene ITGB6 and LTBP1 may be associated with diabetic kidney disease progression and immune cell infiltration

This study suggests that cuproptosis-related genes ITGB6 and LTBP1 may be associated with the progression of DKD through their potential role in immune cell infiltration, and could serve as potential novel targets for the prevention and diagnosis of DKD.

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Publication Details

Journal
PeerJ
Published
2025-11-11
DOI
https://doi.org/10.7717/peerj.20346
Primary Topic
Ferroptosis and cancer prognosis
Type
article
Field-Weighted Citation Impact
0.00
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article

The cuproptosis-related gene ITGB6 and LTBP1 may be associated with diabetic kidney disease progression and immune cell infiltration

Wenjia Hu, Jing Xu, Shiqiang Liu, Suying Hu et al.
PeerJ
Ferroptosis and cancer prognosis
article

The cuproptosis-related gene ITGB6 and LTBP1 may be associated with diabetic kidney disease progression and immune cell infiltration

Wenjia Hu, Jing Xu, Shiqiang Liu, Suying Hu, Mengdi Tian, Wei Shen, Zhen Wang, Ying Tang, Qing‐Yu He, Lei Ji, Liang Yao, Feifei Fan, Huan Yao
article en

Abstract

This study suggests that cuproptosis-related genes ITGB6 and LTBP1 may be associated with the progression of DKD through their potential role in immune cell infiltration, and could serve as potential novel targets for the prevention and diagnosis of DKD.

PeerJVol. 13
Wannan Medical College (CN), Xi'an International Studies University (CN), Honghu Hospital of Traditional Chinese Medicine (CN), First Affiliated Hospital of Wannan Medical College (CN)
Openalex Percentile: Top 52%
Ferroptosis and cancer prognosis
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