Comparative risk of fibrosis progression with sodium-glucose cotransporter-2 vs. dipeptidyl peptidase-4 inhibitors in metabolic dysfunction-associated steatotic liver disease and type 2 diabetes mellitus with low-to-intermediate fibrosis

SGLT2i use was associated with reduced risk of fibrotic progression compared to DPP4i use in adults with MASLD and T2DM.

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Publication Details

Journal
Clinical and Molecular Hepatology
Published
2025-11-11
DOI
https://doi.org/10.3350/cmh.2025.0825
Primary Topic
Liver Disease Diagnosis and Treatment
Type
article
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article

Comparative risk of fibrosis progression with sodium-glucose cotransporter-2 vs. dipeptidyl peptidase-4 inhibitors in metabolic dysfunction-associated steatotic liver disease and type 2 diabetes mellitus with low-to-intermediate fibrosis

Daniel Fulop, Jonggi Choi, Raymond T. Chung, Erik Almazan et al.
Clinical and Molecular Hepatology
Liver Disease Diagnosis and Treatment
article

Comparative risk of fibrosis progression with sodium-glucose cotransporter-2 vs. dipeptidyl peptidase-4 inhibitors in metabolic dysfunction-associated steatotic liver disease and type 2 diabetes mellitus with low-to-intermediate fibrosis

Daniel Fulop, Jonggi Choi, Raymond T. Chung, Erik Almazan, Vy H. Nguyen, Allison J. Carroll, Eric M. Przybyszewski, Jiunn Song, Tracey G. Simon, Megan Michta
article en

Abstract

SGLT2i use was associated with reduced risk of fibrotic progression compared to DPP4i use in adults with MASLD and T2DM.

Clinical and Molecular HepatologyVol. 32(1)
Ulsan College (KR), Brigham and Women's Hospital (US), Harvard University (US), Asan Medical Center (KR), University of Ulsan (KR), Massachusetts General Hospital (US)
Openalex Percentile: Top 56%
Liver Disease Diagnosis and Treatment
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Comparative risk of fibrosis progression with sodium-glucose cotransporter-2 vs. dipeptidyl peptidase-4 inhibitors in metabolic dysfunction-associated steatotic liver disease and type 2 diabetes mellitus with low-to-intermediate fibrosis — Daniel Fulop, Jonggi Choi, et al. · Clinical and Molecular Hepatology (2025) | TGRS Research Map | TGRS