Thermogenic Gene Expression in Human Neck Adipose Tissue in Relation to Circulating and Local Thyroid Hormone Levels
Local regulation of THs may play a role in human adipose tissue thermogenic activity. Pathway-level transcriptomic analysis may better capture these effects than single-gene approaches. Deep neck adipose tissue can serve as a practical model for studying BAT function and endocrine regulation in humans.
Authors
- Alina Gavrila (ORCID: https://orcid.org/0000-0002-3474-3975)
- Sean D. Kodani (ORCID: https://orcid.org/0000-0001-9204-7620)
- Rita A. Monahan-Earley
- Yu‐Hua Tseng (ORCID: https://orcid.org/0000-0003-2053-9559)
- John M. Asara (ORCID: https://orcid.org/0000-0001-7450-2589)
- Benjamin C. James (ORCID: https://orcid.org/0000-0003-2844-8360)
- Aaron M. Cypess (ORCID: https://orcid.org/0000-0002-5570-9346)
- Henrique Camara (ORCID: https://orcid.org/0000-0001-7300-1416)
- Natalia Chaves (ORCID: https://orcid.org/0000-0001-9193-9774)
- Shaelah Huntington
- Lupo Ramón Méndez Durán (ORCID: https://orcid.org/0009-0009-6562-3210)
Institutions
- Joslin Diabetes Center (US)
- Beth Israel Deaconess Medical Center (US)
- Diabetes Australia (AU)
- Clinical Research Management (US)
Publication Details
- Journal
- Journal of the Endocrine Society
- Published
- 2025-11-06
- DOI
- https://doi.org/10.1210/jendso/bvaf178
- Primary Topic
- Adipose Tissue and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Beth Israel Deaconess Medical Center
- National Institutes of Health
- National Center for Advancing Translational Sciences