Neonatal management of parvovirus B19-induced hydrops fetalis: a case report

This case contributes to the limited evidence on postnatal management of B19V-related NIHF. PD may be considered in neonates with persistent, refractory edema despite maximal conventional therapy, with careful individualization of treatment. Further research, including multicenter registries and controlled studies, is needed to define its role within standardized neonatal care protocols.

Authors

Luisa Patanè (ORCID: https://orcid.org/0000-0001-7613-5866)
Laura Lorioli
Roberto Pagani (ORCID: https://orcid.org/0000-0001-7828-6537)
Maurizio Cheli (ORCID: https://orcid.org/0000-0003-1953-278X)
Marco Colombo (ORCID: https://orcid.org/0000-0002-4335-4250)
Giovanna Mangili

Institutions

University of Siena (IT)
Ospedale Papa Giovanni XXIII (IT)
Azienda Ospedaliera Universitaria Senese (IT)
University of Milano-Bicocca (IT)

Publication Details

Journal: Frontiers in Pediatrics
Published: 2025-11-11
DOI: https://doi.org/10.3389/fped.2025.1611058
Primary Topic: Parvovirus B19 Infection Studies
Type: article
Field-Weighted Citation Impact: 0.00

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article

Neonatal management of parvovirus B19-induced hydrops fetalis: a case report

Luisa Patanè, Laura Lorioli, Roberto Pagani, Maurizio Cheli et al.

Nov 11, 2025

Frontiers in Pediatrics

Parvovirus B19 Infection Studies

article

Neonatal management of parvovirus B19-induced hydrops fetalis: a case report

Luisa Patanè, Laura Lorioli, Roberto Pagani, Maurizio Cheli, Marco Colombo, Giovanna Mangili

November 11, 2025article en

Abstract

This case contributes to the limited evidence on postnatal management of B19V-related NIHF. PD may be considered in neonates with persistent, refractory edema despite maximal conventional therapy, with careful individualization of treatment. Further research, including multicenter registries and controlled studies, is needed to define its role within standardized neonatal care protocols.

Frontiers in PediatricsVol. 13

University of Siena (IT), Ospedale Papa Giovanni XXIII (IT), Azienda Ospedaliera Universitaria Senese (IT), University of Milano-Bicocca (IT)

Openalex Percentile: Top 61%

Parvovirus B19 Infection Studies

DOI Open Access PDF OpenAlex

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Neonatal management of parvovirus B19-induced hydrops fetalis: a case report — Luisa Patanè, Laura Lorioli, et al. · Frontiers in Pediatrics (2025) | TGRS Research Map | TGRS