Automated Thoracolumbar Stump Rib Detection and Analysis in a Large CT Cohort
Thoracolumbar stump ribs are one of the essential indicators of thoracolumbar transitional vertebrae or enumeration anomalies. While some studies manually assess these anomalies and describe the ribs qualitatively, this study aims to automate thoracolumbar stump rib detection and analyze their morphology quantitatively. To this end, we train a high-resolution deep learning model for rib segmentation using nnUNet and achieve significant improvements over existing models (Dice score 0.997 vs. 0.779, p-value < 0.01). In addition, we employ a novel iterative algorithm and piecewise linear interpolation to estimate rib length, achieving a success rate of 98.2%. When analyzing morphological features, we show that stump ribs articulate more posteriorly at the vertebrae (−19.2±3.8 vs. −13.8±2.5 mm, p-value < 0.01), are thinner (260.6±103.4 vs. 563.6±127.1mm2, p-value < 0.01), and are oriented more downwards and sideways within the first centimeters in contrast to full-length ribs. We show that with partially visible ribs, these features can achieve an F1-score of 0.84 and an AUC of 0.98 in differentiating stump ribs from regular ones. We publish the model weights and masks for public use.
Authors
- Bjoern Menze (ORCID: https://orcid.org/0000-0003-4136-5690)
- Jan S. Kirschke (ORCID: https://orcid.org/0000-0002-7557-0003)
- Matan Atad (ORCID: https://orcid.org/0000-0001-6952-517X)
- Rickmer Braren
- Friederike Jungmann (ORCID: https://orcid.org/0000-0002-9600-4094)
- Robert Graf (ORCID: https://orcid.org/0000-0001-6656-3680)
- Hendrik Möller (ORCID: https://orcid.org/0009-0001-1978-5894)
- Alina Dima (ORCID: https://orcid.org/0000-0001-8743-3236)
- Johannes C. Paetzold (ORCID: https://orcid.org/0000-0002-4844-6955)
- Florian Kofler (ORCID: https://orcid.org/0000-0003-0642-7884)
- Daniel Rueckert
- H. Schön
- Benjamin Keinert-Weth
Institutions
- Universität Hamburg (DE)
- German Cancer Research Center (DE)
- University of Zurich (CH)
- Cornell University (US)
- TUM Klinikum (DE)
- University Medical Center Hamburg-Eppendorf (DE)
- University of Rostock (DE)
- Imperial College London (GB)
- Technical University of Munich (DE)
Publication Details
- Journal
- AI
- Published
- 2026-06-16
- DOI
- https://doi.org/10.3390/ai7060224
- Primary Topic
- Medical Imaging and Analysis
- Type
- preprint
- Field-Weighted Citation Impact
- 0.00
Funders
- European Research Council