Prognostic Factors for Relapse and the Role of Maintenance Therapy in Acute Promyelocytic Leukemia: A Real-World Multicenter Study in Korea
These findings highlight prognostic factors for relapse and the importance of individualized therapeutic strategies for high-risk patients. Moreover, our findings indicate that post-consolidation MRD is the most significant predictor of relapse, emphasizing the need for molecular profiling and longitudinal monitoring. Future prospective studies should validate these prognostic markers and refine personalized therapeutic approaches for APL.
Authors
- Min Ji Jeon (ORCID: https://orcid.org/0000-0002-1297-107X)
- Mihee Kim (ORCID: https://orcid.org/0000-0002-6258-7287)
- Ka‐Won Kang (ORCID: https://orcid.org/0000-0003-1462-0502)
- Byung‐Hyun Lee (ORCID: https://orcid.org/0000-0003-0603-7923)
- Ho‐Young Yhim (ORCID: https://orcid.org/0000-0002-1252-5336)
- Yong Park (ORCID: https://orcid.org/0000-0001-7909-6639)
- Se Ryeon Lee
- Kunye Kwak (ORCID: https://orcid.org/0009-0005-5908-2607)
- Seo-Yeon Ahn
- Chul Won Choi (ORCID: https://orcid.org/0000-0002-3032-4239)
- Dongjin Shin (ORCID: https://orcid.org/0009-0005-4578-6531)
- Yoon Seok Choi (ORCID: https://orcid.org/0000-0002-0616-7122)
- Byung‐Soo Kim (ORCID: https://orcid.org/0000-0003-0054-8570)
- Chang‐Hoon Lee (ORCID: https://orcid.org/0000-0001-9960-1524)
- Dae Sik Kim (ORCID: https://orcid.org/0000-0001-8424-8561)
- Eun Sang Yu (ORCID: https://orcid.org/0000-0003-2196-0732)
- Jae-Sook Ahn (ORCID: https://orcid.org/0000-0003-0782-2261)
- Hwa Jung Sung
- Changgon Kim (ORCID: https://orcid.org/0000-0002-1975-2486)
Institutions
- Korea University (KR)
- Korea University Medical Center (KR)
- Ansan University (KR)
- Chonnam National University Hwasun Hospital (KR)
- Korea University (JP)
- Jeonbuk National University (KR)
Publication Details
- Journal
- Cancer Research and Treatment
- Published
- 2025-11-10
- DOI
- https://doi.org/10.4143/crt.2025.929
- Primary Topic
- Retinoids in leukemia and cellular processes
- Type
- article
- Field-Weighted Citation Impact
- 0.00