Isoastragaloside I improves hyperglycaemia and increases β‐cell mass in mice
Our results suggest that IAS-I increases β-cell mass and promotes the formation of β-cells from pancreatic ductal cells in vivo. It is also speculated to possess islet-protective activity. These findings provide insight into the potential application of Astragalus membranaceus monomers in diabetic treatment.
Authors
- Tongsheng Zhang (ORCID: https://orcid.org/0000-0001-5783-2367)
- Miao Liu (ORCID: https://orcid.org/0000-0003-0597-8393)
- Chun‐Bo Teng
- Qian Wang (ORCID: https://orcid.org/0000-0002-1355-1616)
- Yuhan Chen (ORCID: https://orcid.org/0000-0002-3307-2903)
- Shuting Zhang (ORCID: https://orcid.org/0000-0002-4051-1038)
- A. Gómez Pan
- Huan Wu (ORCID: https://orcid.org/0000-0002-8689-0379)
Institutions
- Northeast Forestry University (CN)
Publication Details
- Journal
- Diabetic Medicine
- Published
- 2025-11-09
- DOI
- https://doi.org/10.1111/dme.70162
- Primary Topic
- Traditional Chinese Medicine Analysis
- Type
- article
- Field-Weighted Citation Impact
- 0.00