Association of systemic inflammatory biomarkers with prostate cancer risk: a population-based (NHANES) and clinical validation study
Systemic inflammatory biomarkers, particularly composite indices such as SIRI and PIV, are strongly associated with PCa risk and demonstrate nonlinear relationships with PSA parameters. These biomarkers may enhance risk stratification for PCa and serve as non-invasive tools to complement existing diagnostic approaches.
Authors
- Xiongbing Lu (ORCID: https://orcid.org/0000-0001-7313-6126)
- Kaiwen Xiao (ORCID: https://orcid.org/0000-0002-8154-6050)
- Guoqiang Huang (ORCID: https://orcid.org/0000-0003-1491-8309)
- Shuangquan Lin (ORCID: https://orcid.org/0000-0003-4933-0230)
Institutions
- Nanchang University (CN)
- Second Affiliated Hospital of Nanchang University (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-11-10
- DOI
- https://doi.org/10.3389/fendo.2025.1697617
- Citations
- 1
- Primary Topic
- Inflammatory Biomarkers in Disease Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 1.05
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Jiangxi Province