Sweet’s syndrome with Koebner phenomenon triggered by G-CSF as a preleukemic manifestation in a patient with primary myelofibrosis: a case report

Among patients with complex underlying diseases such as myelofibrosis and receiving G-CSF treatment, Sweet's syndrome may not only be an adverse reaction caused by drugs, but more likely to be an early manifestation of leukemia. At this time, SS is a complex comprehensive disease caused by multiple factors. It is not advisable to simply diagnose its phenotype. Instead, a comprehensive assessment should be conducted to reduce misdiagnosis and missed diagnosis. Therefore, in clinical practice, we should strengthen multidisciplinary collaboration even more and enhance the understanding of Sweet's syndrome itself and its role as a potential early warning signal of leukemia. This enables the early identification of diseases and the adoption of effective treatment measures. Although the Koebner phenomenon is relatively rare in SS, its occurrence should be highly valued.